PONIARD PHARMACEUTICALS APPOINTS FOUR NEW MEMBERS TO CLINICAL ADVISORY BOARD
These esteemed physicians will add to the already broad expertise of the Company's Clinical Advisory Board and bring an understanding of a wide variety of tumor types, including prostate, breast, ovarian, head and neck and lung cancers, to inform the development of picoplatin. Picoplatin, the Company's lead product candidate, is a new generation platinum chemotherapy agent with the potential to address multiple indications, combinations and formulations.
"These renowned physicians are experts in several different indications
and will provide strategic input into our clinical development program for
picoplatin, which is being developed as a platform product with broad
applicability across multiple solid tumor types," said
The new Clinical Advisory Board members join existing members
New Clinical Advisory Board Members
-- Howard A. (Skip) Burris, III, M.D., is chief medical officer and
director of drug development at The Sarah Cannon Research Institute in
Nashville, where he is also an associate with Tennessee Oncology, PLLC.
Dr. Burris' research interests focus on developing investigational
agents and evaluating these compounds in Phase 1 and 2 clinical trials.
He has published papers on taxanes and topoisomerase I inhibitors. He
currently serves on the American Society of Clinical Oncology (ASCO)
Board of Directors and is a member of ASCO's Ethics Committee. He
received his medical degree from the University of South Alabama and
completed his residency and fellowship in hematology/oncology at Brooke
Army Medical Center in San Antonio. While there, he served as director
of clinical research at the Institute for Drug Development of The
Cancer Therapy and Research Center and was an associate professor at
The University of Texas Health Science Center.
-- E. David Crawford, M.D., is the E. David Crawford distinguished
professor of surgery, urology and radiation oncology, and head of the
Section of Urologic Oncology at the University of Colorado Health
Sciences Center in Denver. He also serves as the senior associate
director of the University of Colorado Comprehensive Cancer Center in
Denver. Dr. Crawford, the recipient of nearly 70 research grants, has
conducted research in the treatment of advanced bladder cancer,
metastatic adenocarcinoma of the prostate, hormone refractory prostate
cancer, and other areas of urological infections and malignancies. He
has authored or co-authored more than 450 articles published in
peer-reviewed journals and has published five textbooks and authored
more than 50 book chapters. He is an editorial reviewer or consultant
for many publications, including Urology, Journal of Urology, The New
England Journal of Medicine, Cancer and the Journal of Clinical
Oncology. Dr. Crawford is a member of the American Urological
Association (AUA), for which he was a member of the Prostate Cancer
Clinical Trials Subcommittee. He currently serves on the board of
governors, the GU committee, and the scientific advisory board of the
Southwest Oncology Group and chairs the National Prostate Cancer
Education Council. He received his medical degree from the University
of Cincinnati and completed an internship and residency in urology at
the Good Samaritan Hospital in Cincinnati. He completed a genitourinary
cancer fellowship at the University of California Medical Center in Los
Angeles.
-- Robert F. Ozols, M.D., Ph.D., is senior vice president of Fox Chase
Cancer Center in Philadelphia, where he oversees all of the Center's
patient care, clinical research and medical science laboratory
research. Internationally recognized for his expertise in ovarian
cancer, Dr. Ozols' research focuses on how cancer cells develop
resistance to anticancer drugs and on developing new chemotherapy
regimens for ovarian cancer. He previously served on the Oncologic
Drugs Advisory Committee (ODAC) of the Food and Drug Administration. He
is a former vice president of the International Gynecologic Cancer
Society and served on the Board of Directors of the American Society of
Clinical Oncology and the American Association of Cancer Institutes. He
is past chair of ASCO's Cancer Research Committee and of the Cancer
Communications Committee. He is the author of many scientific
publications and has served on the editorial boards of the
International Journal of Gynecologic Cancer, International Journal of
Oncology, Cancer Research, Cancer Investigation, Journal of
Experimental Therapeutics and Oncology and Clinical Cancer Research. He
earned his bachelor's degree in chemistry, Ph.D. and M.D. from the
University of Rochester. He completed his medical training at
Dartmouth-Hitchcock Medical Center and a medical oncology fellowship at
the National Cancer Institute.
-- Everett E. Vokes, M.D., is the John E. Ultmann Professor of Medicine
and Radiation and Cellular Oncology at the University of Chicago
Pritzker School of Medicine; director of the Section of
Hematology/Oncology; vice chairman for clinical research in the
Department of Medicine; director of the head and neck oncology program;
and deputy director of the University of Chicago Cancer Research
Center. He serves as chair of the Cancer and Leukemia Group B,
Respiratory Core Committee. He is the recipient of numerous research
grants and has authored more than 300 publications in peer-reviewed
journals. He received his medical degree from the University of Bonn
Medical School in West Germany and completed his residency at
Ravenswood Hospital in Chicago and at the University of Southern
California in Los Angeles. He completed a fellowship in
hematology/oncology at the University of Chicago.
About Poniard Pharmaceuticals
Poniard Pharmaceuticals, Inc. is a biopharmaceutical company focused on the development and commercialization of innovative oncology products to impact the lives of people with cancer. Picoplatin, the Company's lead platform product candidate, is a new generation platinum therapy with an improved safety profile relative to existing platinum-based cancer therapies. Picoplatin is designed to overcome platinum resistance associated with chemotherapy in solid tumors, and is being studied in multiple cancer indications, combinations and formulations. Clinical trials of intravenous picoplatin include a Phase 3 trial in small cell lung cancer and Phase 2 trials in metastatic colorectal and hormone-refractory prostate cancers, as well as a clinical trial of oral picoplatin in solid tumors. Picoplatin has not been approved by any regulatory authority for use in humans. For additional information please visit http://www.poniard.com.
This release contains forward-looking statements, including statements
regarding the Company's business objectives and strategic goals, drug
development plans, results of clinical trials and the potential safety and
efficacy of its products in development. The Company's actual results may
differ materially from those indicated in these forward-looking statements
based on a number of factors, including risks and uncertainties associated
with the Company's research and development activities; the results of
pre-clinical and clinical testing; the receipt and timing of required
regulatory approvals; the market's acceptance of the Company's proposed
products; the Company's anticipated operating losses, need for future capital
and ability to obtain future funding; competition from third parties; the
Company's ability to preserve and protect intellectual property rights; the
Company's dependence on third-party manufacturers and suppliers; the Company's
lack of sales and marketing experience; the Company's ability to attract and
retain key personnel; changes in technology, government regulation and general
market conditions; and the risks and uncertainties described in the Company's
current and periodic reports filed with the Securities and Exchange Commission
(SEC), including the Company's Annual Report on Form 10-K for the year ended
(C) 2008 Poniard Pharmaceuticals, Inc. All Rights Reserved.
Poniard and Poniard Pharmaceuticals are trademarks of Poniard Pharmaceuticals, Inc.
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